Yes, it is absolutely possible! One can be allergic – or hypersensitive – to a partner’s semen. Learn more about it by listening to our Kinsey Confidential podcast.
The question was:
"When I have sex and my boyfriend ejaculates inside me, I get a bad burning feeling in my vagina. Assuming we’re STI-free, could I be allergic to his semen?"
And my response? Listen here: